Sexual Assault Nurse Examiner (SANE) A Practice Exam

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What is the duration of the NPEP course?

14 days
21 days
28 days
30 days

The correct answer is: 28 days

The duration of the NPEP (Non-Occupational Post-Exposure Prophylaxis) course is typically set at 28 days. This timeframe is grounded in guidelines established for the administration of post-exposure prophylaxis in cases of potential exposure to HIV. The 28-day regimen is designed to maximize the effectiveness of the treatment and is established based on the optimal duration needed to achieve sufficient drug concentration in the bloodstream to prevent seroconversion. The choice of 28 days is supported by studies showing that early and consistent adherence to the medication over this period significantly increases the likelihood of a successful outcome in preventing HIV infection after potential exposure. Understanding this standard duration is crucial for healthcare providers to ensure proper patient education and adherence to the regimen, thereby enhancing public health efforts to combat HIV transmission.